Publication:
EXPLORING THE RELATIONSHIP BETWEEN GENETIC VULNERABILITY AND ADDICITION IN DRUG-INDUCED PSYCHOSIS

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Date
2026-04-16
Authors
Martinez, Sophia
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Poster
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The primary question of this study is whether a family history of psychosis and an increased risk for an individual who struggles with addiction to experience drug-induced psychosis? The study aims to identify what drug-induced psychosis is and how it differs from other variations of psychosis, while exploring underlying factors. The overall research is a literature review of three separate sources with a patient sampling ranging from 48-148 individuals. The first study discovered there are risk factors, such as drug use, that can increase and individual’s likelihood of developing this disease. While the second study focuses on a family history of psychosis and substance abuse, both separated and combined in individuals, to identify id one influences the other. The final study was a comparison of individuals who had primary psychosis with comorbid drug abuse and drug-induced psychosis: Diagnostic and clinical evolution at follow-up. The study revealed that overall, both groups showed similar diagnosis stability over time. There was no evidence that symptoms in drug-induced psychosis groups improved more after stopping substance abuse. Collectively, the evidence suggests that a family history of psychosis and a history of substance abuse are independent factors. Indicating a family history does not directly influence the likelihood of developing drug-induced psychosis if the individual is struggling with addiction. While these factors may not directly influence each other, both of them can increase the risk of the individual experiencing drug-induced psychosis.
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